Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104418 | 0.80 | ALOX15 (0.38) | ALDH1A1SMN1; SMN2ERAP1MEN1KMT2A | |
| SCHEMBL1274800 | 0.79 | NPSR1 (0.52) | NPSR1ALDH1A1SMN1; SMN2MAPTERAP1 | |
| SCHEMBL1274802 | 0.79 | NPSR1 (0.52) | NPSR1ALDH1A1SMN1; SMN2MAPTERAP1 | |
| SCHEMBL4435261 | 0.73 | NPSR1 (0.46) | NPSR1ALDH1A1SMN1; SMN2MAPTCYP4F2 | |
| SCHEMBL243441 | 0.73 | NPSR1 (0.46) | NPSR1ALDH1A1SMN1; SMN2MAPTCYP4F2 | |
| SCHEMBL7547696 | 0.71 | NPSR1 (0.47) | NPSR1ALDH1A1MAPTCYP4F2CYP4A11 | |
| SCHEMBL595761 | 0.69 | NPSR1 (0.45) | NPSR1ALDH1A1SMN1; SMN2MAPTCYP4F2 | |
| SCHEMBL1772581 | 0.69 | NPSR1 (0.48) | NPSR1ALDH1A1SMN1; SMN2MAPTCYP4F2 | |
| SCHEMBL28766822 | 0.69 | NPSR1 (0.48) | NPSR1ALDH1A1SMN1; SMN2MAPTCYP4F2 | |
| SCHEMBL240008 | 0.69 | NPSR1 (0.48) | NPSR1ALDH1A1SMN1; SMN2MAPTCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | NPSR1 1467/4885ALDH1A1 1963/4885SMN1; SMN2 3027/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | NPSR1 4490/4885ALDH1A1 1279/4885SMN1; SMN2 3724/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | NPSR1 4271/4885ALDH1A1 1073/4885SMN1; SMN2 3508/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | NPSR1 1897/4885ALDH1A1 1610/4885SMN1; SMN2 3800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.