SCHEMBL754793

SCHEMBL754793

Cc1ccc(C)c(CS(=O)(=O)C(Br)Br)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
NR3C1 P04150 2/20 0.41
NR3C2 P08235 2/20 0.41
POLB P06746 1/20 0.37
HTT P42858 3/20 0.35
GAA P10253 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
TP53 P04637 2/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PKM P14618 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL753514 0.78 ALDH1A1 (0.44) TAAR1NR3C1NR3C2GAALMNA
SCHEMBL4875195 0.76 TAAR1 (0.52) TAAR1NR3C1NR3C2POLBHTT
SCHEMBL4878296 0.76 TAAR1 (0.52) TAAR1NR3C1NR3C2POLBHTT
SCHEMBL11541776 0.76 TAAR1 (0.47) TAAR1NR3C1NR3C2POLBHTT
SCHEMBL12601886 0.76 TAAR1 (0.47) TAAR1NR3C1NR3C2POLBHTT
SCHEMBL751782 0.73 KMT2A (0.49) POLBGAALMNAALDH1A1MAPT
SCHEMBL754601 0.73 LMNA (0.37) POLBHTTGAALMNAALDH1A1
SCHEMBL11183336 0.71 TAAR1 (0.43) TAAR1NR3C1NR3C2POLBHTT
SCHEMBL269825 0.69 TAAR1 (0.58) TAAR1NR3C1NR3C2POLBHTT
SCHEMBL29462885 0.69 TAAR1 (0.58) TAAR1NR3C1NR3C2POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US claimed
US-8287631-B2 Compounds for preventing ghost odour THOR GMBH (DE) 2012-10-16 US disclosed
US-20100186631-A1 Compounds for preventing ghost odour THOR GMBH (DE) 2010-07-29 US disclosed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone MBTD1, MPST, B2M TAAR1 2058/4885NR3C1 4114/4885NR3C2 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.