Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 4/20 | 0.48 |
| ▸ | PRKCA | P17252 | 4/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.48 |
| ▸ | PRKCG | P05129 | 3/20 | 0.48 |
| ▸ | PRKCH | P24723 | 3/20 | 0.48 |
| ▸ | PRKCI | P41743 | 3/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005333 | 0.89 | PRKCB (0.56) | PRKCBPRKCAPRKCEMEN1TP53 | |
| Acetic Acid SCHEMBL7014928 | 0.87 | PRKCB (0.54) | PRKCBPRKCAPRKCEMEN1TP53 | |
| SCHEMBL7012175 | 0.87 | RPS6KB1 (0.59) | PRKCBPRKCAPRKCEMEN1TP53 | |
| SCHEMBL6982166 | 0.82 | PRKCB (0.51) | PRKCBPRKCAPRKCEMEN1TP53 | |
| SCHEMBL7007889 | 0.82 | CAMK2D (0.62) | PRKCBPRKCAPRKCEMEN1TP53 | |
| Trifluoroacetic Acid SCHEMBL6984632 | 0.77 | PRKCB (0.46) | PRKCBPRKCAPRKCEMEN1TP53 | |
| Trifluoroacetic Acid SCHEMBL7011017 | 0.77 | CAMK2D (0.54) | PRKCBPRKCAPRKCEMEN1TP53 | |
| SCHEMBL7009039 | 0.75 | PRKACA (0.62) | PRKCBPRKCAPRKCEMEN1TP53 | |
| SCHEMBL6981937 | 0.75 | CAMK2D (0.56) | PRKCBPRKCAPRKCEMEN1TP53 | |
| SCHEMBL7004902 | 0.75 | CAMK2D (0.56) | PRKCBPRKCAPRKCEMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192150-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000078750-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-28 | — | — | WO | disclosed |