Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7540742 | 0.99 | HTR2A (0.48) | HTR2ADRD2DRD4DRD3CYP1A2 | |
| Hydrochloric Acid SCHEMBL7547168 | 0.93 | HTR2A (0.48) | HTR2ADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL7546623 | 0.84 | HTR2A (0.45) | HTR2ADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL7544871 | 0.79 | ADRA1A (0.59) | HTR2ADRD2DRD3CYP1A2ADRA1A | |
| SCHEMBL7543096 | 0.79 | DRD2 (0.58) | DRD2DRD4DRD3CYP1A2ADRA1A | |
| SCHEMBL7542176 | 0.79 | HTR2A (0.45) | HTR2ADRD2DRD4DRD3CYP1A2 | |
| Hydrochloric Acid SCHEMBL7540811 | 0.78 | DRD2 (0.57) | DRD2DRD4DRD3CYP1A2ADRA1A | |
| SCHEMBL7540827 | 0.77 | DRD2 (0.67) | DRD2DRD4DRD3CYP1A2ADRA1A | |
| SCHEMBL30440801 | 0.77 | DRD2 (0.67) | DRD2DRD4DRD3CYP1A2ADRA1A | |
| SCHEMBL7547852 | 0.77 | DRD2 (0.67) | DRD2DRD4DRD3CYP1A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883599-B1 | AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | ASTRAZENECA AB (SE) | 2002-06-05 | — | — | EP | claimed |