Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449714 | 0.86 | MMP9 (0.38) | MMP9MMP8ATMTDP1MAPT | |
| SCHEMBL7448681 | 0.86 | KMT2A (0.40) | MMP9MMP8ATMMEN1KMT2A | |
| SCHEMBL7453353 | 0.84 | CNR1 (0.38) | MMP9MMP8ATMTDP1MAPT | |
| SCHEMBL7453006 | 0.83 | NPC1 (0.40) | TDP1MAPTPOLBMEN1NPC1 | |
| SCHEMBL7449950 | 0.82 | ALDH1A1 (0.41) | MAPTPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL7258751 | 0.81 | ATM (0.40) | ATMPTGER1MEN1NPC1ALDH1A1 | |
| SCHEMBL7452291 | 0.81 | MEN1 (0.37) | MMP9MMP8ATMPTGER1POLB | |
| SCHEMBL7448880 | 0.80 | PTGER1 (0.37) | MMP9MMP8ATMCTSLCTSB | |
| SCHEMBL7827665 | 0.80 | APLNR (0.37) | TDP1POLBMEN1KMT2A | |
| SCHEMBL7264011 | 0.80 | MCHR1 (0.39) | MAPTPTGER1S1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |