Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448837 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL7457342 | 0.87 | KMT2A (0.40) | ALDH1A1KMT2AKDM4EHPGDCASP1 | |
| SCHEMBL7449545 | 0.87 | KMT2A (0.40) | ALDH1A1KMT2AKDM4EHPGDCASP1 | |
| SCHEMBL7453006 | 0.85 | NPC1 (0.40) | ALDH1A1MAPTKMT2AKDM4EXIAP | |
| SCHEMBL7449714 | 0.83 | MMP9 (0.38) | MAPTPOLB | |
| SCHEMBL7448681 | 0.83 | KMT2A (0.40) | KMT2AHPGDMEN1USP2LMNA | |
| SCHEMBL7548111 | 0.82 | MMP9 (0.35) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL7453353 | 0.81 | CNR1 (0.38) | MAPTKMT2AHPGDMEN1LMNA | |
| SCHEMBL7263594 | 0.81 | RAB9A (0.43) | ALDH1A1MAPTKDM4EMCL1POLB | |
| SCHEMBL7827665 | 0.80 | APLNR (0.37) | KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |