SCHEMBL7548193 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NCEH1	Q6PIU2	10/20	0.37

▸	ACHE	P22303	3/20	0.36

▸	NPC1	O15118	2/20	0.34

▸	RAB9A	P51151	2/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	TSHR	P16473	2/20	0.33

▸	PKM	P14618	1/20	0.33

▸	LMNA	P02545	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7548189	0.73	NPC1 (0.38)	NCEH1ACHENPC1RAB9AALDH1A1
SCHEMBL8829228	0.71	NCEH1 (0.36)	NCEH1ACHENPC1RAB9AALDH1A1
SCHEMBL16965115	0.59	RAB9A (0.60)	NCEH1NPC1RAB9AALDH1A1TSHR
SCHEMBL29728576	0.58	NCEH1 (0.72)	NCEH1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL16965718	0.58	NCEH1 (0.72)	NCEH1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL7442264	0.58	KDM4E (0.36)	—
SCHEMBL28007495	0.58	NCEH1 (0.58)	NCEH1ACHENPC1RAB9AALDH1A1
SCHEMBL29728586	0.58	NCEH1 (0.54)	NCEH1NPC1RAB9ATSHRPKM
SCHEMBL16965297	0.58	NCEH1 (0.54)	NCEH1NPC1RAB9ATSHRPKM
SCHEMBL9038396	0.57	PTPN1 (0.37)	ALDH1A1SMN1; SMN2TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1996038435-A1	DOPAMINE AGONISTS	ABBOTT LABORATORIES (US)	1996-12-05	—	—	WO	disclosed