⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144679 | 1.00 | — | — | |
| SCHEMBL7548244 | 0.79 | MAOA (0.37) | — | |
| SCHEMBL7548249 | 0.79 | MAOA (0.37) | — | |
| SCHEMBL1162503 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL4121654 | 0.74 | — | — | |
| SCHEMBL6594792 | 0.74 | — | — | |
| SCHEMBL1038154 | 0.74 | MAPT (0.41) | — | |
| SCHEMBL4396833 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL141824 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL8161643 | 0.73 | MAOA (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213080-B1 | HYDROGENATED PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-05-20 | — | — | EP | claimed |
| US-4939160-A | Nootropic agents | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | claimed |
| EP-0213080-B1 | HYDROGENATED PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-05-20 | — | — | EP | disclosed |
| US-4939160-A | Nootropic agents | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| US-4833169-A | MEMORY ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1989-05-23 | — | — | US | disclosed |
| EP-0213080-A2 | Hydrogenated pyridine derivatives | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |