SCHEMBL7541702

SCHEMBL7541702

COC(=O)c1ccc2oc(COc3ccc(NC(C)=O)c(C)c3)nc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.45
ALOX5AP P20292 1/20 0.43
FEN1 P39748 1/20 0.43
RAB9A P51151 3/20 0.40
ALDH1A1 P00352 3/20 0.40
NPC1 O15118 2/20 0.40
LMNA P02545 4/20 0.39
RXFP1 Q9HBX9 1/20 0.39
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.38
ALOX5 P09917 1/20 0.38
EPHX2 P34913 1/20 0.38
THRB P10828 1/20 0.38
GSTP1 P09211 1/20 0.38
KDM4E B2RXH2 2/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
PIK3CG P48736 1/20 0.38
PI4KB Q9UBF8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541433 0.92 MAPT (0.46) MAPTRAB9AALDH1A1NPC1LMNA
SCHEMBL7547344 0.92 ALOX5AP (0.43) MAPTALOX5APFEN1RAB9AALDH1A1
SCHEMBL7548836 0.89 MAPT (0.46) MAPTRAB9AALDH1A1NPC1LMNA
SCHEMBL7542942 0.88 AGPAT2 (0.43) MAPTRAB9AALDH1A1NPC1LMNA
SCHEMBL7541140 0.86 LMNA (0.53) MAPTRAB9AALDH1A1NPC1LMNA
SCHEMBL7547636 0.86 DRD2 (0.46) MAPTLMNARXFP1TP53ALOX5
SCHEMBL7544987 0.86 MAPT (0.56) MAPTALOX5APFEN1RAB9AALDH1A1
SCHEMBL7542425 0.85 ALOX5 (0.48) MAPTALOX5APRAB9ANPC1LMNA
SCHEMBL7543761 0.84 MAPT (0.46) MAPTRAB9AALDH1A1NPC1LMNA
SCHEMBL7541056 0.83 CETP (0.44) ALOX5EPHX2GSTP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed