Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL6753323 | 0.97 | LMNA (0.59) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| Azelaic Acid SCHEMBL11379325 | 0.92 | HDAC3 (0.58) | LMNAKMT2AMEN1HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL3128260 | 0.92 | UNG (0.49) | KMT2AMEN1UNGCYP1A2TSHR | |
| Sebacic Acid SCHEMBL5669870 | 0.92 | HDAC3 (0.58) | LMNAKMT2AMEN1HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL5165477 | 0.92 | HDAC3 (0.58) | LMNAKMT2AMEN1HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL261197 | 0.90 | LMNA (0.68) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| Terephthalic Acid SCHEMBL3334284 | 0.90 | HDAC3 (0.55) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| Terephthalic Acid SCHEMBL262199 | 0.90 | LMNA (0.68) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| Terephthalic Acid SCHEMBL11416033 | 0.90 | LMNA (0.68) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| Azelaic Acid SCHEMBL10980744 | 0.88 | HDAC3 (0.62) | LMNANFKB1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020084654-A1 | Resin connector | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2002-07-04 | — | — | US | claimed |
| CN-115279833-B | Polyamide resin composition | 东洋纺MC株式会社 | 2024-05-17 | — | — | CN | disclosed |
| US-20220411581-A1 | SEMI-AROMATIC POLYAMIDE RESIN COMPOSITION AND METAL-PLATED MOLDED BODY | TOYOBO CO., LTD. (JP) | 2022-12-29 | — | — | US | disclosed |
| CN-115279833-A | Polyamide resin composition | 东洋纺株式会社 | 2022-11-01 | — | — | CN | disclosed |
| CN-111133038-B | Molded article comprising semi-aromatic polyamide resin composition as component | 东洋纺株式会社 | 2022-10-14 | — | — | CN | disclosed |
| CN-114585688-A | Semi-aromatic polyamide resin composition and metal plating molded body | 东洋纺株式会社 | 2022-06-03 | — | — | CN | disclosed |
| WO-2020166482-A1 | CARBON FIBER-REINFORCED POLYAMIDE RESIN COMPOSITION, AND MOLDED ARTICLE THEREOF | 東洋紡株式会社 | 2020-08-20 | — | — | WO | disclosed |
| CN-111133038-A | Molded article comprising semi-aromatic polyamide resin composition as component | 东洋纺株式会社 | 2020-05-08 | — | — | CN | disclosed |
| US-10072137-B2 | Polyamide resin composition having high melt point and being excellent in anti-vibration property upon water absorption | TOYOBO CO., LTD. (JP) | 2018-09-11 | — | — | US | disclosed |
| US-20160130424-A1 | POLYAMIDE RESIN COMPOSITION HAVING HIGH MELT POINT AND BEING EXCELLENT IN ANTI-VIBRATION PROPERTY UPON WATER ABSORPTION | TOYOBO CO., LTD. (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20020084654-A1 | Resin connector | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2002-07-04 | — | — | US | disclosed |