Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740733 | 1.00 | KMT2A (0.35) | KMT2AHPGDRORCOPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL5616268 | 0.99 | KMT2A (0.34) | KMT2AHPGDRORCOPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL757174 | 0.99 | KMT2A (0.34) | KMT2AHPGDRORCOPRD1OPRM1 | |
| SCHEMBL757090 | 0.91 | MAPT (0.36) | KMT2AHPGDOPRD1OPRM1OPRK1 | |
| SCHEMBL757580 | 0.91 | MAPT (0.36) | KMT2AHPGDOPRD1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL755877 | 0.90 | MAPT (0.35) | KMT2AHPGDOPRD1OPRM1OPRK1 | |
| SCHEMBL764691 | 0.89 | ADORA3 (0.40) | OPRD1OPRM1OPRK1OPRL1ADORA3 | |
| SCHEMBL755429 | 0.80 | BACE1 (0.34) | OPRD1OPRM1OPRL1ADORA3ADORA1 | |
| SCHEMBL760030 | 0.80 | BACE1 (0.34) | OPRD1OPRM1OPRL1ADORA3ADORA1 | |
| SCHEMBL755862 | 0.80 | BACE1 (0.34) | OPRD1OPRM1OPRL1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723533-B1 | ATHLETIC SHOE WITH A SHELL INSERTED BETWEEN THE UPPER AND A COMFORT SOLE | NORTH FACE APPAREL CORP (US) | 2024-07-17 | — | — | EP | claimed |
| EP-4103802-B1 | GLASS DOOR WITH A HANDLE ASSEMBLY | REHAU BEHR AS (DK) | 2024-03-27 | — | — | EP | claimed |
| EP-3469419-B1 | INTEGRATION OF ELECTROCHROMIC FILMS ON A SUBSTRATE | FURCIFER INC (US) | 2023-11-29 | — | — | EP | claimed |
| EP-3873545-B1 | MULTI-LAYER BAG WITH LOSS OF INTEGRITY MEANS OF DETECTION | BECTON DICKINSON FRANCE (FR) | 2023-11-29 | — | — | EP | claimed |
| EP-3281626-B1 | SOLUBLE MICRONEEDLE FOR DELIVERING POORLY-SOLUBLE DRUG | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2023-08-23 | — | — | EP | claimed |
| EP-3956390-B1 | METHOD FOR SURFACE FUNCTIONALISATION IN A SUPERCRITICAL FLUID MEDIUM | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2023-08-09 | — | — | EP | claimed |
| EP-3522825-B1 | IMPLANTABLE DEVICES FOR DRUG DELIVERY WITH REDUCED BURST RELEASE | TITAN PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | claimed |
| EP-3801100-B1 | METHODS FOR FORMING FOOTWEAR USING RECYCLED PLASTICS | NIKE INNOVATE CV (US) | 2023-02-22 | — | — | EP | claimed |
| EP-3720914-B1 | AQUEOUS COATING COMPOSITIONS FOR FORMING ANTI-GRAIN-PUFFING COATINGS ON WOOD SUBSTRATE, AQUEOUS PAINTS AND ARTICLES | GUANGDONG HUARUN PAINTS CO LTD (CN) | 2023-02-01 | — | — | EP | claimed |
| EP-3001478-B1 | ENCAPSULATION FILM AND METHOD FOR ENCAPSULATING ORGANIC ELECTRONIC DEVICE USING SAME | LG CHEMICAL LTD (KR) | 2023-01-18 | — | — | EP | claimed |
| WO-2007147811-A2 | METHOD FOR PRODUCING THIN LAYERS OF A SILICON, AND THIN SILICON | HUHTAMAKI FORCHHEIM ZWEIGNIEDERLASSUNG DER HUHTAMAKI DEUTSCHLAND GMBH & CO KG (DE) | 2007-12-27 | — | — | WO | claimed |
| EP-1668088-B1 | ADHESIVE ARTICLES COMPRISING A NANOPARTICLE PRIMER AND METHODS FOR PREPARING SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2007-10-31 | — | — | EP | claimed |
| US-20070021454-A1 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease | MERCK SHARP & DOHME LLC | 2007-01-25 | — | — | US | claimed |
| WO-2007011833-A2 | SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2007-01-25 | — | — | WO | claimed |
| WO-2007011810-A1 | SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2007-01-25 | — | — | WO | claimed |
| EP-1661686-A2 | Method of manufacturing a thin layer of silicone, thin silicone layer and application | Huhtamaki Forchheim Zweigniederlassung der Huhtamaki Deutschland GmbH & Co. KG (DE) | 2006-05-31 | — | — | EP | claimed |
| EP-1178925-B1 | BALLISTIC RESISTANT PANEL AND METHOD OF MAKING | SURVIVAL INC (US) | 2004-11-10 | — | — | EP | claimed |
| EP-1018423-B1 | Tough heat shrinkable film structures | AMERICAN NAT CAN CO (US) | 2003-05-28 | — | — | EP | claimed |
| EP-0567125-B1 | Pre-cooked food product package | VISKASE CORP (US) | 1996-10-23 | — | — | EP | claimed |
| EP-0141108-B1 | PLASTICS SHEET BASED ON VINYL CHLORIDE HOMOPOLYMERS AND/OR COPOLYMERS | J. H. Benecke AG (DE) | 1989-04-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021454-A1 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease | BACE1, APP, PSEN1 | KMT2A 4150/4885HPGD 825/4885RORC 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.