Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 5/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315264 | 0.85 | KDM4A (0.36) | DRD2CA12CA1CA7CA14 | |
| SCHEMBL8829266 | 0.78 | ELANE (0.34) | MAPTELANELMNANPSR1 | |
| Hydrochloric Acid SCHEMBL7309711 | 0.78 | ELANE (0.34) | MAPTELANELMNANPSR1 | |
| SCHEMBL7446408 | 0.75 | DRD2 (0.35) | DRD2ACACBMAPTKDM1AMAOB | |
| Hydrochloric Acid SCHEMBL7447474 | 0.74 | DRD2 (0.35) | DRD2ACACBMAPTKDM1AMAOB | |
| SCHEMBL7548189 | 0.72 | NPC1 (0.38) | LMNAALDH1A1PKMTSHRSMN1; SMN2 | |
| SCHEMBL7311250 | 0.70 | ACHE (0.33) | ELANE | |
| SCHEMBL7447921 | 0.68 | KMT2A (0.38) | ATMKMT2A | |
| SCHEMBL7447927 | 0.68 | KMT2A (0.38) | ATMKMT2A | |
| Hydrochloric Acid SCHEMBL7440751 | 0.68 | KMT2A (0.37) | ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038435-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-12-05 | — | — | WO | disclosed |