SCHEMBL755207

SCHEMBL755207

O=C(O)C=Cc1ccc2cc(C=CC(=O)O)ccc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.64
HSD17B10 Q99714 3/20 0.64
CA12 O43570 3/20 0.64
CA1 P00915 3/20 0.64
CA2 P00918 3/20 0.64
CA3 P07451 3/20 0.64
CA4 P22748 3/20 0.64
CA6 P23280 3/20 0.64
CA5A P35218 3/20 0.64
CA7 P43166 3/20 0.64
CA9 Q16790 3/20 0.64
CA14 Q9ULX7 3/20 0.64
CA5B Q9Y2D0 3/20 0.64
MAPK1 P28482 3/20 0.64
AKR1B10 O60218 2/20 0.64
AKR1B1 P15121 2/20 0.64
DPP4 P27487 2/20 0.64
HDAC3 O15379 2/20 0.64
HDAC4 P56524 2/20 0.64
HDAC1 Q13547 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8746669 1.00 KDM4E (0.64) KDM4EHSD17B10CA12CA1CA2
SCHEMBL11139376 0.93 KDM4E (0.62) KDM4EHSD17B10CA12CA1CA2
SCHEMBL8746632 0.93 KDM4E (0.62) KDM4EHSD17B10CA12CA1CA2
SCHEMBL78427 0.92 RELA (0.62) KDM4EHSD17B10CA12CA1CA2
SCHEMBL29966677 0.92 RELA (0.62) KDM4EHSD17B10CA12CA1CA2
SCHEMBL6552210 0.92 RELA (0.62) KDM4EHSD17B10CA12CA1CA2
SCHEMBL78426 0.92 RELA (0.62) KDM4EHSD17B10CA12CA1CA2
SCHEMBL29462468 0.92 RELA (0.62) KDM4EHSD17B10CA12CA1CA2
SCHEMBL7692268 0.90 CA12 (0.66) KDM4EHSD17B10CA12CA1CA2
SCHEMBL7820626 0.90 HDAC3 (0.59) KDM4EHSD17B10CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8654290-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2014-02-18 US disclosed
EP-2431798-A1 LIQUID CRYSTAL DISPLAY DEVICE Sharp Kabushiki Kaisha (JP) 2012-03-21 EP disclosed
CN-1063182-C New aminophenylphosphonic acid compounds, process for preparing them and pharmaceutical compositions containing them ADIR (FR) 2001-03-14 CN disclosed
US-5670493-A ANGIOGENESIS INHIBITORS ADIR ET COMPAGNIE (FR) 1997-09-23 US disclosed
US-5668148-A BENIGN PROSTATIC HYPERTROPHY MERCK & CO., INC. (US) 1997-09-16 US disclosed
CN-1145908-A New aminophenylphosphonic acid compounds, process for preparing them and pharmaceutical compositions containing them ADIR (FR) 1997-03-26 CN disclosed