SCHEMBL78427

SCHEMBL78427

O=C(O)C=Cc1ccc2ccccc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.62
HDAC3 O15379 2/20 0.61
HDAC4 P56524 2/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC7 Q8WUI4 2/20 0.61
HDAC2 Q92769 2/20 0.61
HDAC10 Q969S8 2/20 0.61
HDAC11 Q96DB2 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
HDAC9 Q9UKV0 2/20 0.61
HDAC5 Q9UQL6 2/20 0.61
TNKS O95271 1/20 0.61
HCAR2 Q8TDS4 1/20 0.61
TNKS2 Q9H2K2 1/20 0.61
CYP3A4 P08684 3/20 0.59
PTPN1 P18031 3/20 0.59
RAB9A P51151 2/20 0.58
CYP1B1 Q16678 2/20 0.57
ESR1 P03372 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29966677 1.00 RELA (0.62) RELAHDAC3HDAC4HDAC1HDAC7
SCHEMBL29462468 1.00 RELA (0.62) RELAHDAC3HDAC4HDAC1HDAC7
SCHEMBL78426 1.00 RELA (0.62) RELAHDAC3HDAC4HDAC1HDAC7
SCHEMBL6552210 1.00 RELA (0.62) RELAHDAC3HDAC4HDAC1HDAC7
Hydrochloric Acid SCHEMBL6781505 0.98 RELA (0.60) RELAHDAC3HDAC4HDAC1HDAC7
SCHEMBL7820626 0.94 HDAC3 (0.59) RELAHDAC3HDAC4HDAC1HDAC7
SCHEMBL7820628 0.94 HDAC3 (0.59) RELAHDAC3HDAC4HDAC1HDAC7
SCHEMBL8746669 0.92 KDM4E (0.64) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL755207 0.92 KDM4E (0.64) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8746632 0.90 KDM4E (0.62) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 858 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3256850-B1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES INC (US) 2025-07-09 EP claimed
CN-119556529-A High-mechanical-strength and high-resolution nano-imprint photoresist and ink-jet printing method thereof 中国科学技术大学 2025-03-04 CN claimed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP claimed
EP-2687568-B1 Adhesive, adhesive tape, and display device SAMSUNG DISPLAY CO LTD (KR) 2018-05-16 EP claimed
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2017-12-21 US claimed
CN-106892911-A A kind of vascular endothelial growth factor receptor inhibitors compound 天津金耀集团有限公司 2017-06-27 CN claimed
CN-104478748-B Optics fluorochemical urethane type acrylate UV curing monomer and manufacture method thereof 哈尔滨工业大学无锡新材料研究院 2016-11-23 CN claimed
EP-1429768-B1 NOVEL MEDICAMENTS FOR INHALATION BOEHRINGER INGELHEIM PHARMA (DE) 2016-11-16 EP claimed
US-20160161475-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION-SENSITIVE FLUORESCENT PROBES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2016-06-09 US claimed
EP-1560861-B1 BLOCK COPOLYMER MELT-PROCESSABLE COMPOSITIONS, METHODS OF THEIR PREPARATION, AND ARTICLES THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2011-09-21 EP claimed
US-20050256149-A1 Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-11-17 US claimed
WO-2005068575-A1 ORIENTATED ACRYLATE ADHESIVE MATERIALS, METHOD FOR THE PRODUCTION AND USE THEREOF TESA AG (DE) 2005-07-28 WO claimed
US-6919325-B2 Respiratory system disorders; synergistic mixtures BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-07-19 US claimed
EP-1429768-A1 NOVEL MEDICAMENTS FOR INHALATION Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2004-06-23 EP claimed
US-20030130300-A1 Respiratory system disorders; synergistic mixtures BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 US claimed
WO-2003024452-A1 NOVEL MEDICAMENTS FOR INHALATION BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2003-03-27 WO claimed
EP-0859819-B1 HEAT-ACTIVATABLE ADHESIVE COMPOSITION MINNESOTA MINING & MFG (US) 1999-12-29 EP claimed
EP-0324480-B1 Photopolymerizable compositions and elements for refractive index imaging DU PONT (US) 1994-04-13 EP claimed
EP-0324481-B1 STORAGE STABLE PHOTOPOLYMERIZABLE COMPOSITION FOR REFRACTIVE INDEX IMAGING E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-05 EP claimed
EP-0324482-B1 PROCESS OF FORMING REFLECTION HOLOGRAMS IN PHOTOPOLYMERIZABLE LAYERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256149-A1 Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts ADRB3, ADRB1, HSD3B1 RELA 2101/4885HDAC3 2896/4885HDAC4 3336/4885
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME CA6, CA13, EPCAM RELA 184/4885HDAC3 2613/4885HDAC4 2195/4885
US-20030130300-A1 Respiratory system disorders; synergistic mixtures ADRB3, ADRB1, CHRM3 RELA 1299/4885HDAC3 2931/4885HDAC4 3462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.