Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574544 | 0.87 | ALDH1A1 (0.41) | NFE2L2ATMNR3C2SMN1; SMN2TSHR | |
| SCHEMBL30057200 | 0.86 | MAPT (0.44) | NR3C2SMN1; SMN2TSHRGAATRPV1 | |
| SCHEMBL7489674 | 0.84 | CA1 (0.46) | ATMNR3C2TSHRGAAMEN1 | |
| SCHEMBL9042759 | 0.78 | AHR (0.50) | AHRMAOBRAB9AMEN1KMT2A | |
| SCHEMBL7032980 | 0.77 | ALDH1A1 (0.56) | TSHRMAOBBACE1RAB9AALDH1A1 | |
| SCHEMBL11572643 | 0.74 | CYP1A1 (0.42) | NR3C2SMN1; SMN2GAARAB9AMEN1 | |
| SCHEMBL9101266 | 0.73 | MAPT (0.41) | AHRSMN1; SMN2GAANPSR1MEN1 | |
| SCHEMBL8102819 | 0.73 | CYP1A2 (0.43) | GAACA12CA1CA2CA7 | |
| SCHEMBL7123446 | 0.73 | RELA (0.42) | NFE2L2AHRSMN1; SMN2MAOBGAA | |
| SCHEMBL5901796 | 0.73 | CA12 (0.42) | NFE2L2GAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713486-B1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 2002-07-17 | — | — | EP | disclosed |
| US-5623005-A | NAPTHOPYRAN COMPOUNDS CONTAINING AMINE SUBSTITUTION AT 6-POSITION; USEFUL TO MAKE OPHTHALMIC LENS | PILKINGTON PLC (GB) | 1997-04-22 | — | — | US | disclosed |
| EP-0691965-B1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-12-04 | — | — | EP | disclosed |
| EP-0713486-A1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 1996-05-29 | — | — | EP | disclosed |
| US-5520853-A | LIGHT SENSITIVE COMPOUNDS FOR POLYMERS OR CELLULOSE DERIVATIVES FOR LENSES | PILKINGTON PLC (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0691965-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1995005371-A1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994022850-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1994-10-13 | — | — | WO | disclosed |