Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.41 |
| ▸ | HPGD | P15428 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101496 | 0.81 | MEN1 (0.39) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL9100003 | 0.80 | MAPT (0.42) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL11574544 | 0.75 | ALDH1A1 (0.41) | KMT2AMEN1POLBALDH1A1GAA | |
| SCHEMBL7489674 | 0.75 | CA1 (0.46) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL30057200 | 0.74 | MAPT (0.44) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL9258680 | 0.73 | RAB9A (0.41) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL7552122 | 0.73 | NFE2L2 (0.43) | KMT2AMEN1ALDH1A1GAANPSR1 | |
| SCHEMBL7817042 | 0.71 | ERN1 (0.39) | MAPTKMT2AMEN1NPC1KDM4E | |
| SCHEMBL31558552 | 0.71 | NPC1 (0.50) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL8718999 | 0.70 | KMT2A (0.39) | KMT2AMEN1LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552091-A | PHOTOCHROMIC, LENSES | PPG INDUSTRIES, INC. (US) | 1996-09-03 | — | — | US | disclosed |