Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.80 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.80 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.80 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.77 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.77 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.77 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553077 | 1.00 | PDK1 (0.80) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL9111491 | 0.90 | ALOX15 (0.78) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL9110299 | 0.90 | ALOX15 (0.78) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL9905245 | 0.90 | ALOX15 (0.78) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL5134413 | 0.89 | PDK1 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL5134412 | 0.89 | PDK1 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL9111475 | 0.89 | PDK1 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL11479944 | 0.88 | HSD17B10 (0.74) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL11479951 | 0.88 | HSD17B10 (0.74) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL5711211 | 0.87 | PDK1 (0.83) | PDK1PDK2PDK3PDK4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155496-A1 | Saturated and unsaturated abietane derivatives, derived conjugates and uses in a diagnostic composition, a reagent and a device | BIO MERIEUX (FR) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155496-A1 | Saturated and unsaturated abietane derivatives, derived conjugates and uses in a diagnostic composition, a reagent and a device | C1R, CBR1, CNR1 | PDK1 2748/4885PDK2 4309/4885PDK3 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.