SCHEMBL752310

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13754947	0.90	KCNH2 (0.56)	KCNH2MAP2K7ALDH1A1HPGDHSD17B10
	SCHEMBL13754981	0.81	KCNH2 (0.47)	KCNH2MAP2K7BACE1NOS1ESR1
	SCHEMBL27756279	0.81	KCNH2 (0.47)	KCNH2MAP2K7BACE1NOS1ESR1
	SCHEMBL6810696	0.81	HTR2A (0.54)	KCNH2BACE1NOS1
	SCHEMBL3432650	0.81	MAP2K7 (0.44)	KCNH2MAP2K7KDM4EALDH1A1HPGD
	SCHEMBL752939	0.78	KCNH2 (0.47)	KCNH2MAP2K7KDM4EALDH1A1HPGD
	SCHEMBL755313	0.77	TAAR1 (0.58)	TDP1KCNH2MAP2K7ALDH1A1EGFR
	SCHEMBL757063	0.76	L3MBTL1 (0.58)	KCNH2MAP2K7KDM4EALDH1A1ESR1
	SCHEMBL752175	0.76	GAA (0.58)	TDP1KCNH2KDM4EALDH1A1ESR1
	SCHEMBL757064	0.76	SIGMAR1 (0.43)	KCNH2KDM4EBACE1NOS1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.