SCHEMBL755435

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23281510	0.82	PDE2A (0.49)	LMNAPOLBMAPTSMN1; SMN2NPC1
	SCHEMBL14724360	0.75	CYP1A2 (0.49)	MEN1KMT2ALMNAHTTPOLB
	SCHEMBL18590774	0.75	PTGS1 (0.42)	KMT2AHTTALDH1A1MAOBPTGS1
	SCHEMBL753980	0.73	HDAC1 (0.51)	MEN1KMT2ALMNAHTTPOLB
	SCHEMBL28119890	0.71	MEN1 (0.57)	MEN1KMT2ANPC1RAB9AMAOB
	SCHEMBL13278686	0.71	MAOB (0.48)	MEN1KMT2ANPC1RAB9ATSHR
	SCHEMBL757316	0.70	MAOB (0.53)	MAOBAPP
	SCHEMBL19328802	0.70	MAOB (0.49)	MEN1KMT2ANPC1RAB9AMAOB
	SCHEMBL26971276	0.70	MEN1 (0.45)	MEN1KMT2ALMNAHTTPOLB
	SCHEMBL13530312	0.69	ALDH1A1 (0.41)	MEN1KMT2ALMNAHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.