SCHEMBL753980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25542583	0.86	HDAC1 (0.47)	HDAC1HDAC8HDAC6HDAC5NPC1
	SCHEMBL753735	0.83	L3MBTL1 (0.47)	HDAC1HDAC8HDAC6HDAC5MAPK1
	SCHEMBL2893216	0.81	MEN1 (0.46)	MEN1KMT2ANPC1RAB9ALMNA
	SCHEMBL8278886	0.77	LMNA (0.45)	MEN1KMT2ANPC1RAB9ALMNA
	SCHEMBL27448990	0.76	L3MBTL1 (0.46)	MEN1KMT2AKDM4EL3MBTL1POLB
	SCHEMBL755435	0.73	MEN1 (0.46)	MEN1KMT2ANPC1RAB9ALMNA
	SCHEMBL24351052	0.72	NUDT1 (0.39)	HDAC1HDAC8HDAC6HDAC5NPC1
	SCHEMBL16453460	0.72	NOS3 (0.43)	MEN1KMT2ANPC1RAB9ALMNA
	SCHEMBL754204	0.71	MAPT (0.42)	MEN1KMT2ANPC1RAB9ALMNA
	SCHEMBL27741979	0.70	ALDH1A1 (0.58)	MEN1KMT2ANPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.