Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.56 |
| ▸ | MMP9 | P14780 | 4/20 | 0.56 |
| ▸ | MMP13 | P45452 | 4/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315168 | 0.88 | LMNA (0.46) | MMP1MMP9MMP13ADAM17KDM4E | |
| SCHEMBL7311620 | 0.82 | FFAR4 (0.52) | MMP1MMP9MMP13ADAM17KDM4E | |
| SCHEMBL7311421 | 0.80 | MMP1 (0.81) | MMP1MMP9MMP13ADAM17KDM4E | |
| SCHEMBL7323224 | 0.79 | MMP1 (0.57) | MMP1MMP9MMP13ADAM17LMNA | |
| SCHEMBL7324177 | 0.73 | FFAR4 (0.47) | MMP1MMP9MMP13ADAM17ALDH1A1 | |
| SCHEMBL7317773 | 0.72 | FFAR4 (0.53) | MMP1MMP9MMP13ADAM17ALDH1A1 | |
| SCHEMBL7316361 | 0.72 | MMP9 (0.79) | MMP1MMP9MMP13ADAM17LMNA | |
| SCHEMBL7319166 | 0.72 | MMP9 (1.00) | MMP1MMP9MMP13ADAM17MMP12 | |
| SCHEMBL27529783 | 0.71 | MMP9 (0.62) | MMP1MMP9MMP13ADAM17KDM4E | |
| SCHEMBL7315611 | 0.71 | MMP9 (0.57) | MMP1MMP9MMP13ADAM17MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938471-B1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID CO (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0938471-A1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | American Cyanamid Company (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998016503-A2 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |