Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | FCER2 | P06734 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799243 | 0.71 | MMP1 (0.49) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL4421137 | 0.71 | MMP1 (0.49) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL6801897 | 0.65 | MMP1 (0.41) | MMP1FCER2MMP2MMP3MMP7 | |
| Methyl 3-Phenylpropanoate SCHEMBL28250358 | 0.65 | TDP1 (0.54) | HPGDALDH1A1LMNAPKMKMT2A | |
| SCHEMBL7559682 | 0.65 | MMP8 (0.41) | MMP8MEN1KMT2A | |
| SCHEMBL7559383 | 0.62 | TDP1 (0.40) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL7554484 | 0.61 | MMP3 (0.40) | MMP3MMP9HPGDPOLBALDH1A1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL28249480 | 0.61 | TDP1 (0.60) | MAPTLMNAPKMMEN1KMT2A | |
| SCHEMBL4573219 | 0.60 | MMP1 (0.41) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL4573215 | 0.60 | MMP1 (0.41) | MMP1FCER2MMP2MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925278-B1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 2002-07-17 | — | — | EP | claimed |