Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13694071 | 0.80 | GHSR (0.50) | SCN4ACTSCPOLB | |
| SCHEMBL13694045 | 0.80 | GHSR (0.50) | SCN4ACTSCPOLB | |
| SCHEMBL10060310 | 0.79 | MEN1 (0.49) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL18142154 | 0.79 | CTSC (0.49) | CTSCHTR2CHTR2BTAAR1ELANE | |
| Proline SCHEMBL9015317 | 0.78 | CTSC (0.51) | SCN4ACTSCHTR2CHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL11100316 | 0.78 | SCN4A (0.48) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL13436116 | 0.77 | MEN1 (0.53) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL4677228 | 0.76 | EPHX2 (0.49) | CTSCHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6968209 | 0.75 | L3MBTL1 (0.48) | SCN4ACTSCHTR2CHTR2BOPRM1 | |
| SCHEMBL7309838 | 0.75 | SCN4A (0.47) | SCN4ACTSCHTR2CHTR2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3340981-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017035353-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |