SCHEMBL7557008

SCHEMBL7557008

O=C(OC1(CO)CCC(CO)CC1)c1cccc(C(=O)OC2(CO)CCC(CO)CC2)c1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
IL1B P01584 1/20 0.33
P2RX7 Q99572 1/20 0.33
EPHX1 P07099 1/20 0.32
EPHX2 P34913 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87785 0.88 KMT2A (0.33) SMN1; SMN2IL1BP2RX7EPHX2ALDH1A1
SCHEMBL27342835 0.83 TP53 (0.34) IL1BP2RX7ALDH1A1LMNA
SCHEMBL27819942 0.80 TSHR (0.34) SMN1; SMN2ALDH1A1LMNA
SCHEMBL374008 0.75 LMNA (0.47) SMN1; SMN2ALDH1A1LMNAL3MBTL1
SCHEMBL7560468 0.73 JMJD6 (0.49) CYP4F2CYP4A11L3MBTL1CHRNB2CHRNA4
SCHEMBL2695598 0.70 HSD11B1 (0.32)
Isophthalic Acid SCHEMBL17628646 0.70 KMO (0.50) ALDH1A1
SCHEMBL11403082 0.69
SCHEMBL7789361 0.69 NR1H4 (0.46) CHRNB2CHRNA4
SCHEMBL7798853 0.68 RAB9A (0.37) SMN1; SMN2NPSR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4056504-A GLASS FIBERS, POLYALKYLENE GLYCOL TEREPHTHALATE OR ISOPHTHALATE ION BAYER AKTIENGESELLSCHAFT (DT) 1977-11-01 US claimed
EP-0889922-B1 APPARATUS AND PROCESS FOR A POLYCONDENSATION REACTION DU PONT (US) 2002-07-24 EP disclosed
EP-0934323-B1 SOLUBLE MONO-ALKYL STANNOIC ACID CATALYST AND ITS USE IN PREPARING HIGH MOLECULAR WEIGHT POLYESTERS DU PONT (US) 2001-12-12 EP disclosed
EP-0724607-B1 CONTINUOUS POLYESTER PROCESS DU PONT (US) 1999-08-04 EP disclosed
US-5891985-A Soluble mono-alkyl stannoic acid catalyst and its use in preparing high molecular weight polyesters E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-06 US disclosed
EP-0889922-A1 APPARATUS AND PROCESS FOR A POLYCONDENSATION REACTION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-13 EP disclosed
US-5856423-A Apparatus and process for a polycondensation reaction E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-05 US disclosed
US-5849849-A Polyesters production process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-15 US disclosed
US-5811496-A Process for polymerization of polyester oligomers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-22 US disclosed
WO-1997035902-A9 APPARATUS AND PROCESS FOR A POLYCONDENSATION REACTION 1997-12-31 WO disclosed
US-5688898-A Polyesters production process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-18 US disclosed
US-5677415-A Apparatus and process for a polycondensation reaction E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-10-14 US disclosed
WO-1997035902-A1 APPARATUS AND PROCESS FOR A POLYCONDENSATION REACTION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-10-02 WO disclosed
US-5599900-A Polyesters production process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-04 US disclosed
US-5552513-A Atomospheric pressure polyester process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-03 US disclosed
US-5434239-A Esterification, condensation polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-18 US disclosed
US-5296586-A Heating and agitating monomers or oligomers in inert liquid medium at its boiling point, removing volatile products by codistillation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-22 US disclosed