SCHEMBL7557553

SCHEMBL7557553

COc1c(O)c(C)c2c(c1OC)OC(C)(CCCCC(=O)N1CCOCC1)C2

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLA P06280 2/20 0.40
RAB9A P51151 4/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
FKBP1A P62942 2/20 0.36
GAA P10253 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
POLB P06746 3/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 1/20 0.35
USP2 O75604 1/20 0.34
PCNA P12004 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7555648 0.83 IMPDH1 (0.42) CYP1A2CYP3A4KDM4EHPGDLMNA
SCHEMBL7555671 0.83 CYP4F2 (0.37) KDM4EHPGDLMNATSHRALDH1A1
SCHEMBL7554694 0.72 IMPDH2 (0.32) CYP2C9CYP2C19LMNAUSP2
SCHEMBL7971422 0.69 RAB9A (0.48) GLARAB9AL3MBTL1CYP1A2CYP3A4
SCHEMBL7559409 0.68 MEN1 (0.41)
SCHEMBL16274006 0.67 ALOX5 (0.53) CYP1A2CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL9415751 0.64 GLA (0.67) GLARAB9AL3MBTL1CYP1A2CYP3A4
SCHEMBL7694058 0.63 GLA (0.65) GLARAB9AL3MBTL1CYP1A2CYP3A4
SCHEMBL2953470 0.62 GLA (0.93) GLARAB9AL3MBTL1CYP1A2CYP3A4
SCHEMBL10757643 0.62 ALOX5 (0.45) CYP1A2CYP3A4CYP2C9CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0846109-B1 QUINONE COMPOUND, ITS PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-07-24 EP disclosed
US-6011046-A Quinone compound, its production and use as antioxidant TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-01-04 US disclosed
EP-0846109-A1 QUINONE COMPOUND, ITS PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1998-06-10 EP disclosed
WO-1997007109-A1 QUINONE COMPOUND, ITS PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-02-27 WO disclosed