Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977575 | 0.84 | RAB9A (0.46) | RAB9AL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL7974479 | 0.81 | IMPDH1 (0.37) | TSHRPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7971427 | 0.81 | CYP1A2 (0.36) | TSHRALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL7974599 | 0.78 | CYP4F2 (0.44) | L3MBTL1POLBLMNAALDH1A1KDM4E | |
| SCHEMBL7557553 | 0.69 | GLA (0.40) | RAB9AL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL7694058 | 0.68 | GLA (0.65) | RAB9AL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL474080 | 0.67 | L3MBTL1 (0.67) | RAB9AL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL8971899 | 0.67 | L3MBTL1 (0.67) | RAB9AL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL8972298 | 0.67 | L3MBTL1 (0.67) | RAB9AL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL8972353 | 0.67 | L3MBTL1 (0.67) | RAB9AL3MBTL1TSHRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |