SCHEMBL755762

SCHEMBL755762

C=C(C(=O)O)c1ccccn1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
NAPRT Q6XQN6 1/20 0.63
P4HTM Q9NXG6 1/20 0.63
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 1/20 0.55
GSK3B P49841 1/20 0.50
KDM4E B2RXH2 3/20 0.49
NPC1 O15118 2/20 0.49
PKM P14618 2/20 0.49
RAB9A P51151 2/20 0.49
MAPT P10636 1/20 0.49
PTGS2 P35354 1/20 0.46
OPRK1 P41145 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
AGTR1 P30556 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1769091 0.98 LMNA (0.61) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL6611666 0.83 CES2 (0.59) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL18934701 0.83 LMNA (0.56) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL6274156 0.82 KMT2A (0.61) LMNAL3MBTL1NAPRTP4HTMCES2
Glycinebetaine SCHEMBL9741100 0.82 LMNA (0.44) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL3349775 0.82 CES2 (0.57) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL30499331 0.82 CES2 (0.57) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL4336990 0.82 CES2 (0.57) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL1382335 0.82 CES2 (0.57) LMNAL3MBTL1NAPRTP4HTMCES2
SCHEMBL4336992 0.79 LMNA (0.52) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574664-B Ultraviolet-resistant wet heat aging transparent PI hardening coating and preparation method thereof 新恒东薄膜材料(常州)有限公司 2023-08-11 CN claimed
CN-115960365-A Biological terminal hydroxyl hyperbranched polyester, hyperbranched UV (ultraviolet) curing resin, and preparation method and application thereof 上海交通大学 2023-04-14 CN claimed
CN-114058199-B UV-cured super-hydrophilic anti-fog coating and preparation method and application thereof 深圳南科新材科技有限公司 2022-11-08 CN claimed
EP-4043202-A1 ELECTROPLATED NON-ALLERGENIC PT-NI ALLOY AND BATH AND GALVANIC CYCLE THEREOF BLUCLAD S.p.A. (IT) 2022-08-17 EP claimed
CN-112680216-B Fluorescent probe for ammonia detection and preparation method and application of test paper thereof 湖南超亟检测技术有限责任公司 2022-07-08 CN claimed
CN-114058199-A UV-cured super-hydrophilic anti-fog coating and preparation method and application thereof 深圳南科新材科技有限公司 2022-02-18 CN claimed
CN-112680216-A Novel fluorescent probe for ammonia detection and preparation method and application of test paper thereof 湖南超亟化学科技有限公司 2021-04-20 CN claimed
US-10829466-B2 Stilbene derivative and preparation method thereof BEIJING INSTITUTE OF TECHNOLOGY (CN) 2020-11-10 US claimed
US-20200148662-A1 NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF BEIJING INSTITUTE OF TECHNOLOGY (CN) 2020-05-14 US claimed
CN-104694057-A Breaking-resistant acrylate pressure-sensitive adhesive for walls and preparation method thereof CHUZHOU YUNLIN DIGITAL IMAGING SUPPLIES CO LTD 2015-06-10 CN claimed
CN-104694053-A Acrylate pressure sensitive adhesive for walls and preparation method of acrylate pressure sensitive adhesive CHUZHOU YUNLIN DIGITAL IMAGING SUPPLIES CO LTD 2015-06-10 CN claimed
CN-104694041-A Preparation method of gum for wall CHUZHOU YUNLIN DIGITAL IMAGING SUPPLIES CO LTD 2015-06-10 CN claimed
US-8846039-B2 Method for ameliorating pruritus ASAN LABORATORIES COMPANY (CAYMAN), LIMITED (TW) 2014-09-30 US claimed
EP-2033635-A1 Short-chain fatty acid derivatives for treating pruritus Asan Laboratories Company (Cayman) Limited (CN) 2009-03-11 EP claimed
EP-2030616-A1 Short-chain fatty acid derivatives for treating pruritus Asan Laboratories Company (Cayman) Limited (CN) 2009-03-04 EP claimed
US-20080107646-A1 Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier Sunny Pharmtech Inc. (TW) 2008-05-08 US claimed
EP-1085095-A1 Synthesis of optically active phenylalanine analogs through microbial transformations NSC Technologies Company, L.L.C. (US) 2001-03-21 EP claimed
US-5995869-A Reduction of skin sensitization in electrotransport drug delivery ALZA CORPORATION (US) 1999-11-30 US claimed
US-5981239-A USING LYASE FROM RHODOTORULA TO INTRODUCE AMMONIA STEREOSPECIFICALLY INTO DOUBLE BOND OF AN ARYLACRYLIC ACID; AMINO ACID FOR USE IN VIRICIDAL PROTEASE INHIBITORS AGAINST HUMAN IMMUNODEFICIENCY VIRUS, INFLUENZA AND OTHERS GREAT LAKES CHEMICAL CORP. (US) 1999-11-09 US claimed
WO-1997047355-A1 REDUCTION OF SKIN SENSITIZATION IN ELECTROTRANSPORT DRUG DELIVERY ALZA CORPORATION (US) 1997-12-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10829466-B2 Stilbene derivative and preparation method thereof STS, F12, GLB1 LMNA 1887/4885L3MBTL1 4307/4885NAPRT 3528/4885
US-20200148662-A1 NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF STS, F12, STK38L LMNA 1896/4885L3MBTL1 4510/4885NAPRT 3443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.