SCHEMBL18934701

SCHEMBL18934701

C=C(O)C(=C)c1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
P4HTM Q9NXG6 2/20 0.56
NAPRT Q6XQN6 1/20 0.56
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 4/20 0.48
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
CCR6 P51684 1/20 0.46
KDM4E B2RXH2 7/20 0.45
GSK3B P49841 1/20 0.44
GAA P10253 2/20 0.43
GLA P06280 1/20 0.43
PKM P14618 3/20 0.43
POLB P06746 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4336992 0.83 LMNA (0.52) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL755762 0.83 LMNA (0.63) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL9461486 0.81
Hydrochloric Acid SCHEMBL1769091 0.81 LMNA (0.61) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL18934700 0.80 CES2 (0.50) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL19085486 0.80 CES2 (0.50) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL6611666 0.78 CES2 (0.59) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL1408599 0.78 CES2 (0.58) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL6274156 0.78 KMT2A (0.61) LMNAL3MBTL1P4HTMNAPRTCES2
SCHEMBL24454816 0.77 CES2 (0.47) LMNAL3MBTL1P4HTMNAPRTCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220037599-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-02-03 US disclosed
US-20210198298-A1 LUMINESCENT MATERIAL AND ELECTROLUMINESCENT DISPLAY DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2021-07-01 US disclosed
US-20210155647-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-27 US disclosed
EP-3150606-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES CARRYING BENZOFURANE OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2019-08-14 EP disclosed
EP-2857409-B1 Novel Heteroleptic Iridium Complexes UNIVERSAL DISPLAY CORP (US) 2017-08-02 EP disclosed
WO-2017093958-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220037599-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, TLL1, TLL2 LMNA 1791/4885L3MBTL1 13/4885P4HTM 1979/4885
US-20210198298-A1 LUMINESCENT MATERIAL AND ELECTROLUMINESCENT DISPLAY DEVICE USING THE SAME ALDH1A2, CD99, EPB41L2 LMNA 3808/4885L3MBTL1 1694/4885P4HTM 2148/4885
US-20210155647-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND NOM1, MSL1, L1CAM LMNA 1458/4885L3MBTL1 13/4885P4HTM 2034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.