Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345810 | 0.91 | RAB9A (0.45) | LMNAL3MBTL1NAPRTP4HTMNPC1 | |
| SCHEMBL18934701 | 0.83 | LMNA (0.56) | LMNAL3MBTL1NAPRTP4HTMNPC1 | |
| SCHEMBL4341948 | 0.82 | ALDH1A1 (0.48) | LMNAL3MBTL1NAPRTP4HTMNPC1 | |
| SCHEMBL4345805 | 0.82 | CES2 (0.47) | LMNAL3MBTL1NAPRTP4HTMNPC1 | |
| SCHEMBL755762 | 0.79 | LMNA (0.63) | LMNAL3MBTL1NAPRTP4HTMNPC1 | |
| SCHEMBL9461486 | 0.78 | — | — | |
| SCHEMBL596952 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL1769091 | 0.78 | LMNA (0.61) | LMNAL3MBTL1NAPRTP4HTMNPC1 | |
| SCHEMBL19085486 | 0.77 | CES2 (0.50) | LMNAL3MBTL1NAPRTP4HTMNPC1 | |
| SCHEMBL18934700 | 0.77 | CES2 (0.50) | LMNAL3MBTL1NAPRTP4HTMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026380-A1 | MEDICAL DEVICE WITH BIOFUNCTIONALIZED POLYMER COATING | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2009-02-26 | — | — | WO | claimed |