Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558609 | 0.88 | CSNK2A1 (0.40) | CSNK2A1CSNK2A2CSNK2BMAPTPOLB | |
| SCHEMBL8116477 | 0.75 | MAPT (0.42) | CSNK2A1CSNK2A2CSNK2BMAPTPOLB | |
| SCHEMBL9868847 | 0.73 | CSNK2A1 (0.47) | CSNK2A1CSNK2A2CSNK2BMAPTPOLB | |
| SCHEMBL7574968 | 0.72 | BCAT1 (0.43) | USP2TSHR | |
| SCHEMBL8112156 | 0.72 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2CSNK2BMAPTPOLB | |
| SCHEMBL9534239 | 0.70 | CSNK2A1 (0.38) | CSNK2A1CSNK2A2CSNK2BMAPTPOLB | |
| SCHEMBL8112154 | 0.69 | MAPT (0.42) | CSNK2A1CSNK2A2CSNK2BMAPTPOLB | |
| SCHEMBL4782024 | 0.68 | TRAP1 (0.38) | MEN1GAAKMT2AKDM4EHPGD | |
| SCHEMBL7554463 | 0.68 | PDE4A (0.44) | MAPTPOLBTDP1L3MBTL1HSD17B10 | |
| SCHEMBL29362247 | 0.68 | CSNK2A1 (0.36) | CSNK2A1CSNK2A2CSNK2BMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002056681-A2 | NOVEL INTERMEDIATES AND PROCESS TO PYRIMIDINEDIONE HERBICIDES | FMC CORPORATION (US) | 2002-07-25 | — | — | WO | disclosed |