Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221707 | 0.85 | ATM (0.52) | KMT2AATMLMNAMAPTTP53 | |
| SCHEMBL9037994 | 0.75 | TP53 (0.36) | KMT2ALMNATP53ALDH1A1KDM4E | |
| SCHEMBL11781482 | 0.72 | ALDH1A1 (0.49) | KMT2ALMNAMEN1NTRK1IGF1R | |
| SCHEMBL7556878 | 0.72 | ALDH1A1 (0.55) | KMT2AATMALDH1A1NPSR1TDP1 | |
| SCHEMBL9036658 | 0.71 | TP53 (0.37) | TP53NTRK1NTRK2GAAKDM4E | |
| SCHEMBL8813745 | 0.71 | ATM (0.49) | KMT2AATMLMNAMAPTTP53 | |
| SCHEMBL14123260 | 0.71 | ATM (0.63) | KMT2AATMLMNAMAPTMEN1 | |
| SCHEMBL8776029 | 0.70 | BCAT2 (0.39) | — | |
| SCHEMBL28726412 | 0.68 | L3MBTL1 (0.56) | KMT2AATMLMNAMAPTTP53 | |
| SCHEMBL6973438 | 0.68 | HSD17B10 (0.66) | KMT2AATMLMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010334-A1 | Processes to prepare pyrimidinediones | FMC CORPORATION | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010334-A1 | Processes to prepare pyrimidinediones | ALKBH1, CBR1, ALKBH3 | KMT2A 1901/4885ATM 411/4885LMNA 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.