Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999444 | 0.85 | ALDH1A1 (0.34) | PTGS2SLC2A1HTR2AHTR2CHTR2B | |
| SCHEMBL10890233 | 0.83 | ALDH1A1 (0.33) | PTGS2HTR2AHTR2CHTR2BMETAP2 | |
| SCHEMBL7559299 | 0.83 | TRPV1 (0.41) | DRD2GABRA1GABRB2 | |
| SCHEMBL24707377 | 0.83 | MEP1B (0.38) | PTGS2HTR2AHTR2CHTR2BMETAP2 | |
| SCHEMBL2119962 | 0.83 | SLC2A1 (0.33) | PTGS2SLC2A1 | |
| SCHEMBL15427431 | 0.80 | CA1 (0.33) | PTGS2SLC2A1TAAR1GABRA1 | |
| SCHEMBL14999417 | 0.80 | ALOX5AP (0.34) | PTGS2SLC2A1HTR2AALDH1A1 | |
| SCHEMBL28575172 | 0.78 | AR (0.36) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL7594740 | 0.77 | NNMT (0.40) | HTR2BMETAP2KDM4EALDH1A1MAPK1 | |
| SCHEMBL28925024 | 0.77 | NNMT (0.40) | METAP2KDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272761-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-09-22 | — | — | US | disclosed |
| US-8633123-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2014-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272761-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | PTGS2 130/4885SLC2A1 4738/4885HTR2A 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.