Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758424 | 0.79 | GABRR1 (0.40) | KMT2AL3MBTL1 | |
| SCHEMBL6343838 | 0.77 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7703356 | 0.74 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL7127675 | 0.74 | CYP1A2 (0.45) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL31269349 | 0.73 | HSD17B10 (0.33) | RAB9ASMN1; SMN2 | |
| SCHEMBL4436717 | 0.73 | HSD17B10 (0.33) | RAB9ASMN1; SMN2 | |
| SCHEMBL6946789 | 0.73 | HTR2C (0.47) | RAB9ANPC1QPCT | |
| SCHEMBL13373334 | 0.72 | L3MBTL1 (0.64) | RAB9ANPC1SMN1; SMN2L3MBTL1QPCT | |
| SCHEMBL19994540 | 0.72 | L3MBTL1 (0.78) | RAB9ASMN1; SMN2KMT2AL3MBTL1QPCT | |
| SCHEMBL7706327 | 0.71 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2HIF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185542-A2 | PURINE DERIVATIVES | Pfizer Limited (GB) | 2002-03-13 | — | — | EP | claimed |
| WO-2000077018-A2 | PURINE DERIVATIVES | PFIZER LIMITED (GB) | 2000-12-21 | — | — | WO | claimed |