Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESRRG | P62508 | 3/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ESRRB | O95718 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456580 | 0.85 | KCNH2 (0.59) | KCNH2SIGMAR1GRIA4TSHRESRRG | |
| SCHEMBL18905257 | 0.82 | MEN1 (0.40) | KCNH2SIGMAR1ESRRGSLC13A5LMNA | |
| SCHEMBL31573982 | 0.80 | KCNH2 (0.67) | KCNH2SIGMAR1GRIA4TSHRESRRG | |
| SCHEMBL18905280 | 0.79 | RORC (0.38) | KCNH2SIGMAR1GRIA4 | |
| SCHEMBL547138 | 0.78 | KCNH2 (0.53) | KCNH2SIGMAR1GRIA4TSHRESRRG | |
| SCHEMBL14838173 | 0.78 | KCNH2 (0.53) | KCNH2SIGMAR1GRIA4TSHRESRRG | |
| SCHEMBL18905292 | 0.77 | ESR1 (0.38) | KCNH2ESRRGSLC13A5ESRRB | |
| SCHEMBL5346525 | 0.76 | MEN1 (0.62) | KCNH2SIGMAR1GRIA4TSHRESRRG | |
| SCHEMBL697688 | 0.76 | CA2 (0.52) | KCNH2SIGMAR1GRIA4TSHRESRRG | |
| SCHEMBL6547537 | 0.76 | RAB9A (0.56) | KCNH2SIGMAR1ESRRGSLC13A5DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469881-A | [2-(p-t-Butylphenyl)ethyl]silanes and method of making the same | PETRARCH SYSTEMS INC. (US) | 1984-09-04 | — | — | US | claimed |
| CN-110343128-B | Method for preparing silane through hydrosilation reaction | 中国科学院化学研究所 | 2021-02-19 | — | — | CN | disclosed |
| CN-110343128-A | A method of silane is prepared by silicon hydrogenation | 中国科学院化学研究所 | 2019-10-18 | — | — | CN | disclosed |
| EP-2688917-A2 | HYDROSILYATION OF VINYL MACROMERS WITH METALLOCENES | Exxonmobil Chemical Patents Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| US-8501894-B2 | Hydrosilyation of vinyl macromers with metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-08-06 | — | — | US | disclosed |
| WO-2012134726-A2 | HYDROSILYATION OF VINYL MACROMERS WITH METALLOCENES | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20120245300-A1 | Hydrosilyation Of Vinyl Macromers With Metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-09-27 | — | — | US | disclosed |
| EP-0971963-B1 | PI-COMPLEX COMPOUNDS | BAYER AG (DE) | 2002-07-17 | — | — | EP | disclosed |
| EP-0912585-B1 | METALLOCENE COMPOUNDS | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-6184320-B1 | AS POLYMERIZATION CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-06 | — | — | US | disclosed |
| EP-0971963-A1 | PI-COMPLEX COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0912585-A1 | METALLOCENE COMPOUNDS | BAYER AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998045339-A1 | π-COMPLEX COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998001455-A1 | METALLOCENE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-15 | — | — | WO | disclosed |
| US-4469881-A | [2-(p-t-Butylphenyl)ethyl]silanes and method of making the same | PETRARCH SYSTEMS INC. (US) | 1984-09-04 | — | — | US | disclosed |
| US-4469881-A | [2-(p-t-Butylphenyl)ethyl]silanes and method of making the same | PETRARCH SYSTEMS INC. (US) | 1984-09-04 | — | — | US | disclosed |
| US-4469881-A | [2-(p-t-Butylphenyl)ethyl]silanes and method of making the same | PETRARCH SYSTEMS INC. (US) | 1984-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245300-A1 | Hydrosilyation Of Vinyl Macromers With Metallocenes | VIM, VCL, VIL1 | KCNH2 3097/4885SIGMAR1 1882/4885GRIA4 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.