Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230035 | 0.81 | CHRM3 (0.54) | LMNACHRM3CHRM2CHRM1MEN1 | |
| SCHEMBL1670874 | 0.80 | CES2 (0.45) | CHRM3CHRM2CHRM1MEN1POLB | |
| SCHEMBL1951103 | 0.80 | LMNA (0.62) | LMNACHRM3CHRM2CHRM1MAPK1 | |
| SCHEMBL352390 | 0.80 | LMNA (0.62) | LMNACHRM3CHRM2CHRM1MAPK1 | |
| SCHEMBL11878020 | 0.80 | CHRM3 (0.49) | LMNACHRM3CHRM2CHRM1MEN1 | |
| SCHEMBL7564702 | 0.76 | MEN1 (0.46) | LMNACHRM3CHRM2CHRM1MAPK1 | |
| SCHEMBL2687707 | 0.76 | LMNA (0.58) | LMNACHRM3CHRM2CHRM1MAPK1 | |
| SCHEMBL11421308 | 0.74 | KCNN4 (0.37) | LMNAMAPK1MEN1KMT2ACES2 | |
| Benzylic Acid SCHEMBL7559896 | 0.74 | LMNA (0.67) | LMNAMAPK1CNR1CNR2CES2 | |
| SCHEMBL9663474 | 0.73 | LMNA (0.50) | LMNACHRM3CHRM2CHRM1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002067890-A2 | METHOD AND PRODUCT FOR SKIN LIGHTENING | UNILEVER PLC (GB) | 2002-09-06 | — | — | WO | disclosed |