Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559902 | 0.80 | LMNA (0.46) | CES2CES1CHRM3CHRM2CHRM1 | |
| Benzylic Acid SCHEMBL1670871 | 0.78 | CES2 (0.49) | CES2CES1KCNN4ALDH1A1HTT | |
| SCHEMBL1670872 | 0.75 | CES2 (0.46) | CES2CES1MEN1KMT2AKCNN4 | |
| SCHEMBL28230035 | 0.75 | CHRM3 (0.54) | CHRM3CHRM2CHRM1MEN1POLB | |
| SCHEMBL11878020 | 0.74 | CHRM3 (0.49) | CHRM3CHRM2CHRM1MEN1POLB | |
| SCHEMBL7522990 | 0.72 | CES2 (0.56) | CES2CES1MEN1POLBKMT2A | |
| SCHEMBL8410789 | 0.72 | CES2 (0.56) | CES2CES1MEN1POLBKMT2A | |
| SCHEMBL7564702 | 0.71 | MEN1 (0.46) | CHRM3CHRM2CHRM1MEN1POLB | |
| SCHEMBL1671676 | 0.70 | CES2 (0.63) | CES2CES1MEN1POLBKMT2A | |
| SCHEMBL11354965 | 0.70 | CES2 (0.63) | CES2CES1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |