Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Oxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Oxide SCHEMBL3993955 | 1.00 | — | — | |
| Nitric Oxide SCHEMBL7184108 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL2731176 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL6890944 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL2890900 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL37670 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL5104249 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL306589 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL2888647 | 0.87 | — | — | |
| Nitric Oxide SCHEMBL3636459 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 704210 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6435138-B1 | — | — | None | — | — | US | claimed |
| US-6432363-B1 | — | — | None | — | — | US | claimed |
| US-6372642-B1 | — | — | None | — | — | US | claimed |
| US-6436366-B1 | — | — | None | — | — | US | claimed |
| JP-5155626-A | — | — | None | — | — | JP | claimed |
| US-6413885-B1 | — | — | None | — | — | US | claimed |
| US-6423190-B1 | — | — | None | — | — | US | claimed |
| US-9976464-B1 | Reductant spray and exhaust gas flow guide and deflector | GM Global Technology Operations LLC (US) | 2018-05-22 | — | — | US | claimed |
| US-9976462-B2 | Method for the operation of an exhaust gas aftertreatment system | MAN TRUCK & BUS AG (DE) | 2018-05-22 | — | — | US | claimed |
| US-9974451-B2 | System and method for a biosensor monitoring and tracking band | SANMINA CORPORATION (US) | 2018-05-22 | — | — | US | claimed |
| US-3933432-A | Photoionization | HNU SYSTEMS INC. (US) | 1976-01-20 | — | — | US | claimed |
| US-3933979-A | Gas purifying method | METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | claimed |
| US-3933543-A | OXIDIZER, A NON-METAL, A FUEL | ATLANTIC RESEARCH CORPORATION (US) | 1976-01-20 | — | — | US | claimed |
| US-3933478-A | Recovery of zinc and copper from brass scrap | NICOSEP ASSOCIATES (US) | 1976-01-20 | — | — | US | claimed |
| US-3932544-A | CHLORINATION OF 1,4-DICHLORO-BUTENE-2 | PETRO-TEX CHEMICAL CORPORATION (US) | 1976-01-13 | — | — | US | claimed |
| US-3932585-A | CATALYTIC REDUCTION TO NITROGEN | NIPPON KOKAN KABUSHIKI KAISHA (JA) | 1976-01-13 | — | — | US | claimed |
| US-3932598-A | REACTION OF FERROCHROME ALLOY WITH 1A NITRATE OR CARBONATE | COOPER HUGH S | 1976-01-13 | — | — | US | claimed |
| US-3930369-A | Lean prechamber outflow combustor with two sets of primary air entrances | GENERAL MOTORS CORPORATION (US) | 1976-01-06 | — | — | US | claimed |
| US-3931051-A | CATALYST FOR THE OXIDATION OF AMMONIA | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-01-06 | — | — | US | claimed |
| US-3931391-A | LITHIUM DOPED CALCIUM OXIDE CATALYST | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-01-06 | — | — | US | claimed |