SCHEMBL7560368

SCHEMBL7560368

Cc1cc(NC(=O)C(C)c2cc(C(=N)N)ccc2O)ccc1-n1cnc2c1CCCC2

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.40
F9 P00740 5/20 0.40
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
PLAU P00749 7/20 0.33
PRSS1 P07477 3/20 0.33
F2 P00734 3/20 0.33
PLAT P00750 3/20 0.33
THRB P10828 1/20 0.33
PLG P00747 2/20 0.32
KLKB1 P03952 1/20 0.32
ANO1 Q5XXA6 1/20 0.32
HPN P05981 2/20 0.31
ITGB3 P05106 1/20 0.31
ITGA2B P08514 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6940338 0.89 F10 (0.39) F10F9PRSS1F2THRB
Hydrochloric Acid SCHEMBL7570036 0.88 F10 (0.38) F10F9PRSS1F2THRB
SCHEMBL6941666 0.83 F10 (0.39) F10PRSS1F2ANO1
Hydrochloric Acid SCHEMBL7561132 0.82 F10 (0.38) F10PRSS1F2ANO1
SCHEMBL7525875 0.75 F10 (0.47) F10F9PLAUPRSS1F2
SCHEMBL2990398 0.74 F7 (0.35) F2
Hydrochloric Acid SCHEMBL7526160 0.74 F10 (0.46) F10F9PLAUPRSS1F2
SCHEMBL6942560 0.71 F10 (0.37) F10PRSS1F2ANO1
Hydrochloric Acid SCHEMBL7562752 0.70 F10 (0.37) F10PRSS1F2ANO1
SCHEMBL7528831 0.68 F10 (0.46) F10F9PLAUPRSS1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183519-A1 Antithrombotic carboxylic acid amides SERPINC1, TFPI, F2 F10 33/4885F9 10/4885GABRG2 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.