Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | PCSK9 | Q8NBP7 | 5/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL864817 | 0.91 | PCSK9 (0.56) | FLT3PCSK9LOXL2AHRHTR1A | |
| SCHEMBL28338445 | 0.85 | LOXL2 (0.69) | PCSK9LOXL2AHRHRH3 | |
| SCHEMBL29403791 | 0.85 | LOXL2 (0.69) | PCSK9LOXL2AHRHRH3 | |
| SCHEMBL401081 | 0.85 | LOXL2 (0.69) | PCSK9LOXL2AHRHRH3 | |
| SCHEMBL28335219 | 0.83 | LOXL2 (0.67) | PCSK9LOXL2AHRHRH3 | |
| SCHEMBL6994522 | 0.83 | LOXL2 (0.53) | PCSK9LOXL2AHRDPP4GUSB | |
| SCHEMBL6991621 | 0.80 | PCSK9 (0.50) | PCSK9LOXL2AHRDPP4GUSB | |
| SCHEMBL7492821 | 0.80 | PCSK9 (0.53) | FLT3PCSK9LOXL2AHRDPP4 | |
| SCHEMBL7495753 | 0.77 | AHR (0.49) | PCSK9LOXL2AHRGUSBIDO1 | |
| SCHEMBL11811160 | 0.77 | IDO1 (0.49) | FLT3PCSK9LOXL2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080906-A1 | PREVENTION AND TREATMENT OF ENDOMETRIOSIS WITH ARYL HYDROCARBON RECEPTOR BINDING LIGANDS | CEDARS-SINAI MEDICAL CENTER (US) | 2002-10-17 | — | — | WO | disclosed |
| US-20020147155-A1 | Prevention and treatment of endometriosis with aryl hydrocarbon receptor binding ligands | CEDARS-SINAI MEDICAL CENTER | 2002-10-10 | — | — | US | disclosed |