SCHEMBL7560564

SCHEMBL7560564

Ic1cccc(Oc2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.57
TSHR P16473 1/20 0.57
MAOB P27338 1/20 0.56
AKR1C3 P42330 1/20 0.55
HDAC8 Q9BY41 1/20 0.48
MEN1 O00255 1/20 0.46
MITF O75030 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
GFER P55789 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NLRP1 Q9C000 1/20 0.46
NOD2 Q9HC29 1/20 0.46
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
MAOA P21397 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839195 0.93 ALDH1A1 (0.54) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL3839098 0.93 ALDH1A1 (0.54) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL30148759 0.93 ALDH1A1 (0.46) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL3841098 0.93 ALDH1A1 (0.46) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL3845675 0.91 SMN1; SMN2 (0.58) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL3845360 0.90 SMN1; SMN2 (0.50) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL74818 0.88 ALDH1A1 (0.50) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL3840557 0.84 GAA (0.44) LTA4HTSHRMAOBAKR1C3MEN1
SCHEMBL23894336 0.83 ALDH1A1 (0.45) LTA4HTSHRMAOBAKR1C3HDAC8
SCHEMBL805918 0.83 ALDH1A1 (0.45) LTA4HMAOBAKR1C3MEN1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023225457-A1 SAPONIN-BASED IMMUNOSTIMULANTS, PHARMACEUTICAL COMPOSITION COMPRISING SAID IMMUNOSTIMULANTS, THERAPEUTIC USE THEREOF THE UAB RESEARCH FOUNDATION (US) 2023-11-23 WO disclosed
US-20230157163-A1 ORGANIC COMPOUND, PREPARATION METHOD THEREOF, AND DISPLAY PANEL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-18 US disclosed
WO-2023077216-A1 HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS FOR TREATING FUNGAL INFECTIONS AND METHODS OF USE THEREOF BRIGHT ANGEL THERAPEUTICS INC. (CA) 2023-05-11 WO disclosed
EP-3464286-B1 PYRAZOLOPYRIDINE DERIVATIVES FOR THE TREATMENT OF CANCER GENENTECH INC (US) 2021-08-18 EP disclosed
US-11021425-B2 Polybrominated diphenyl-based flame retardant compounds INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-06-01 US disclosed
CN-111233903-A Organic electroluminescent material containing boron and application thereof in organic electroluminescent device 江苏三月光电科技有限公司 2020-06-05 CN disclosed
US-20200115308-A1 POLYBROMINATED DIPHENYL-BASED FLAME RETARDANT COMPOUNDS INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-04-16 US disclosed
EP-2301538-B1 Compounds for nonsense suppression, and methods for their use PTC THERAPEUTICS INC (US) 2015-05-20 EP disclosed
EP-2871180-A1 2-AMINONICOTINIC ACID ESTER DERIVATIVE AND BACTERICIDE CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2015-05-13 EP disclosed
WO-2014207761-A1 TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-12-31 WO disclosed
US-20020172652-A1 Composition for film formation and material for insulating film formation JSR CORPORATION (JP) 2002-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157163-A1 ORGANIC COMPOUND, PREPARATION METHOD THEREOF, AND DISPLAY PANEL HTR4, AR, HTR2C LTA4H 2793/4885TSHR 2340/4885MAOB 274/4885
US-11021425-B2 Polybrominated diphenyl-based flame retardant compounds PCBP1, FBL, PBRM1 LTA4H 2272/4885TSHR 2176/4885MAOB 174/4885
US-20020172652-A1 Composition for film formation and material for insulating film formation VCL, BMI1, PUF60 LTA4H 3926/4885TSHR 4810/4885MAOB 216/4885
US-20200115308-A1 POLYBROMINATED DIPHENYL-BASED FLAME RETARDANT COMPOUNDS PCBP1, FBL, PBRM1 LTA4H 2272/4885TSHR 2176/4885MAOB 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.