Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14077429 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRLMNATDP1 | |
| SCHEMBL7560569 | 0.78 | CA1 (0.44) | SMN1; SMN2CA1CA2HPGDKMT2A | |
| SCHEMBL7560081 | 0.76 | L3MBTL1 (0.46) | SMN1; SMN2CA1CA2HPGDTSHR | |
| SCHEMBL6703692 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2CA1CA2TSHRKMT2A | |
| SCHEMBL10333091 | 0.76 | ALDH1A1 (0.52) | SMN1; SMN2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL5797662 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2CA1CA2TSHRKMT2A | |
| SCHEMBL6157370 | 0.74 | GAA (0.57) | SMN1; SMN2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL6025444 | 0.74 | GAA (0.57) | SMN1; SMN2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL6025442 | 0.74 | GAA (0.57) | SMN1; SMN2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL7564185 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRKMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |