SCHEMBL7561007

SCHEMBL7561007

C=Cc1ccccc1C=S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 1/20 0.39
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
NFE2L2 Q16236 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
MITF O75030 1/20 0.30
CYP1A2 P05177 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
PKM P14618 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30
CCR6 P51684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7638 0.85 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL473080 0.85 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL29405187 0.85 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL9713659 0.85 MEN1 (0.44) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL1176773 0.82 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL11016199 0.82 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL8719955 0.82 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL22496001 0.82 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL9562250 0.82 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
Water SCHEMBL20379011 0.82 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217677-A1 Organic Electronic Device Comprising a Substrate, an Anode Layer, a Cathode Layer, at Least One First Emission Layer, and a Hole Injection Layer That Comprises a Metal Complex NOVALED GMBH (DE) 2023-07-06 US disclosed
US-20230010535-A1 ELECTROACTIVE COMPOUNDS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-01-12 US disclosed
US-10858610-B2 Cold cranking simulator viscosity boosting base stocks and lubricating oil formulations containing the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-12-08 US disclosed
US-20200172675-A1 LOW-COLOR POLYMERS FOR FLEXIBLE SUBSTRATES IN ELECTRONIC DEVICES DUPONT ELECTRONICS, INC. 2020-06-04 US disclosed
US-20020082357-A1 Resin and its use in converting morphine to codeine CORCORAN ROBERT C (US) 2002-06-27 US disclosed
WO-2002028917-A2 RESIN AND ITS USE IN CONVERTING MORPHINE TO CODEINE CORCORAN ROBERT C (US) 2002-04-11 WO disclosed
EP-0516257-B1 Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same SCHERING AG (DE) 1998-08-05 EP disclosed
US-5470854-A Antiestrogens SCHERING AKTIENGESELLSCHAFT (DE) 1995-11-28 US disclosed
WO-1992021669-A1 2-PHENYLBENZO[B]FURANS AND THIOPHENES, METHODS OF PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1992-12-10 WO disclosed
EP-0516257-A1 Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same SCHERING AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082357-A1 Resin and its use in converting morphine to codeine OPRM1, OPRK1, OPRL1 ALDH1A1 1395/4885TSHR 3710/4885MEN1 4170/4885
US-20230010535-A1 ELECTROACTIVE COMPOUNDS NR4A2, NR2C2, ESR2 ALDH1A1 3088/4885TSHR 1089/4885MEN1 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.