Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CRAT | P43155 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6116686 | 0.89 | TGFBR1 (0.36) | TGFBR1 | |
| SCHEMBL6117814 | 0.87 | TGFBR1 (0.36) | TGFBR1KMT2ALMNA | |
| SCHEMBL4779976 | 0.85 | TGFBR1 (0.46) | TGFBR1TSHRCHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL368659 | 0.84 | TGFBR1 (0.44) | TGFBR1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL6116476 | 0.81 | TSHR (0.41) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL2790664 | 0.78 | TGFBR1 (0.38) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL7263360 | 0.77 | TGFBR1 (0.37) | TGFBR1 | |
| SCHEMBL6116566 | 0.76 | TGFBR1 (0.35) | TGFBR1 | |
| SCHEMBL366307 | 0.75 | SLC22A16 (0.38) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL10496364 | 0.74 | TGFBR1 (0.43) | TGFBR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143098-B1 | POLYMER AND SURFACTANT COMPOSITIONS AND THEIR USES FOR THE IMPROVED RECOVERY OF HYDROCARBONS | TOTAL SE (FR) | 2021-02-10 | — | — | EP | claimed |
| CN-116102840-A | Composite asphalt warm mix agent, preparation method and application thereof, asphalt and asphalt mixture | 北京东方雨虹防水技术股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| EP-3143098-B1 | POLYMER AND SURFACTANT COMPOSITIONS AND THEIR USES FOR THE IMPROVED RECOVERY OF HYDROCARBONS | TOTAL SE (FR) | 2021-02-10 | — | — | EP | disclosed |
| EP-3143098-A1 | POLYMER AND SURFACTANT COMPOSITIONS AND THEIR USES FOR THE IMPROVED RECOVERY OF HYDROCARBONS | Total SA (FR) | 2017-03-22 | — | — | EP | disclosed |
| WO-2015173339-A1 | POLYMER AND SURFACTANT COMPOSITIONS AND THEIR USES FOR THE IMPROVED RECOVERY OF HYDROCARBONS | TOTAL SA (FR) | 2015-11-19 | — | — | WO | disclosed |
| EP-1228112-A1 | COPOLYMERS OF ACRYLOYLAMINOALKYL COMPOUNDS | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001019878-A1 | COPOLYMERS OF ACRYLOYLAMINOALKYL COMPOUNDS | CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) | 2001-03-22 | — | — | WO | disclosed |