SCHEMBL815739

SCHEMBL815739

C=CC(=O)Oc1ccc(-c2ccc(CCC)cc2)cc1

nearest known ligand 0.90

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 12/20 0.90
KMT2A Q03164 2/20 0.48
PLA2G1B P04054 1/20 0.48
ATG4B Q9Y4P1 1/20 0.48
ACACB O00763 1/20 0.47
ACACA Q13085 1/20 0.47
MAPT P10636 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
CASP3 P42574 1/20 0.45
RAB9A P51151 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
MCL1 Q07820 1/20 0.44
THRA P10827 7/20 0.44
ALDH1A1 P00352 1/20 0.43
MEN1 O00255 1/20 0.42
PDE6D O43924 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4596017 0.95 THRB (1.00) THRBKMT2APLA2G1BATG4BMAPT
SCHEMBL7787037 0.93 THRB (0.97) THRBKMT2APLA2G1BATG4BMAPT
SCHEMBL14373519 0.92 THRB (0.76) THRBKMT2APLA2G1BATG4BACACB
SCHEMBL14400631 0.92 THRB (0.76) THRBKMT2APLA2G1BATG4BACACB
SCHEMBL823056 0.91 THRB (0.83) THRBKMT2AMAPTTHRAALDH1A1
SCHEMBL7212815 0.90 THRB (0.90) THRBKMT2APLA2G1BATG4BMAPT
SCHEMBL22566602 0.90 THRB (0.72) THRBKMT2ATHRAMEN1PDE6D
SCHEMBL22566502 0.90 THRB (0.72) THRBKMT2ATHRAMEN1PDE6D
SCHEMBL12193436 0.89 THRB (0.91) THRBKMT2AMAPTTHRAALDH1A1
SCHEMBL101905 0.88 THRB (0.89) THRBKMT2AMAPTTHRAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3839008-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-07-26 EP disclosed
EP-3215892-B1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2020-03-18 EP disclosed
EP-2921545-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2019-08-21 EP disclosed
EP-3127989-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-02-08 EP disclosed
EP-2325168-B1 POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND ADEKA CORP (JP) 2014-03-19 EP disclosed
US-8512597-B2 Polymerizable optically active imide compound and polymerizable composition containing the compound ADEKA CORPORATION (JP) 2013-08-20 US disclosed
US-8512597-B2 Polymerizable optically active imide compound and polymerizable composition containing the compound ADEKA CORPORATION (JP) 2013-08-20 US disclosed
US-8168734-B2 Lateral alpha-substituted acrylate compound and polymer thereof JNC CORPORATION (JP) 2012-05-01 US disclosed
US-8057701-B2 Trifunctional (meth)acrylate compound and polymerizable composition containing same ADEKA CORPORATION (JP) 2011-11-15 US disclosed
US-8057701-B2 Trifunctional (meth)acrylate compound and polymerizable composition containing same ADEKA CORPORATION (JP) 2011-11-15 US disclosed
EP-2261201-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND Adeka Corporation (JP) 2010-12-15 EP disclosed
US-7785488-B2 Lateral oxirane compound and polymer thereof CHISSO CORPORATION (JP) 2010-08-31 US disclosed
US-20100032621-A1 POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20100032621-A1 POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20080081133-A1 Trifunctional compound, composition and polymer thereof CHISSO CORPORATION 2008-04-03 US disclosed
US-20070238026-A1 Holographic recording composition, optical recording medium and optical recording method FUJIFILM CORPORATION (JP) 2007-10-11 US disclosed
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof CHISSO CORPORATION 2007-06-14 US disclosed
US-20070134440-A1 Lateral oxirane compound and polymer thereof CHISSO CORPORATION 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081133-A1 Trifunctional compound, composition and polymer thereof OXER1, AFF1, OXGR1 THRB 2863/4885KMT2A 1317/4885PLA2G1B 4380/4885
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME C1S, PYM1, MCCC2 THRB 3247/4885KMT2A 3291/4885PLA2G1B 3522/4885
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof AFF1, CNKSR1, LEF1 THRB 3134/4885KMT2A 922/4885PLA2G1B 3609/4885
US-20100032621-A1 POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS CHRM1, CHRM2, CCNE1 THRB 4880/4885KMT2A 2784/4885PLA2G1B 1277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.