Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.44 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437684 | 0.91 | PLAU (0.64) | KDM4EALOX12PLAUNCF1KMT2A | |
| SCHEMBL31424217 | 0.91 | PLAU (0.64) | KDM4EALOX12PLAUNCF1KMT2A | |
| Hydrochloric Acid SCHEMBL1946689 | 0.89 | PLAU (0.62) | KDM4EALOX12PLAUNCF1KMT2A | |
| Sulfuric Acid SCHEMBL8530640 | 0.81 | KDM4E (0.62) | KDM4EALOX12PLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL7555431 | 0.79 | METAP2 (0.82) | KDM4EALOX12PLAUNCF1KMT2A | |
| SCHEMBL14337175 | 0.78 | PLAU (0.48) | KDM4EALOX12PLAUNCF1KMT2A | |
| SCHEMBL481403 | 0.76 | KDM4E (0.56) | KDM4EALOX12PLAUNCF1KMT2A | |
| Quinoline SCHEMBL27656523 | 0.76 | TSHR (0.54) | KDM4EALOX12PLAUNCF1KMT2A | |
| SCHEMBL29469825 | 0.75 | CA1 (0.59) | PLAUNCF1KMT2ACYP2C9SLC40A1 | |
| SCHEMBL11277247 | 0.75 | KDM4E (0.50) | KDM4EALOX12PLAUNCF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6488750-B1 | Inkless fingerprint compound and method | ARMOR HOLDINGS FORENSICS INC. | 2002-12-03 | — | — | US | disclosed |
| WO-2002092705-A1 | INKLESS FINGERPRINT COMPOUND AND METHOD | ARMOR HOLDINGS FORENSICS, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
| US-20020166477-A1 | INKLESS FINGERPRINT COMPOUND AND METHOD | SAFARILAND, LLC | 2002-11-14 | — | — | US | disclosed |