Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451770 | 1.00 | PKM (0.31) | PKMPLCG1CCR5ALDH1A1MAPT | |
| SCHEMBL7448989 | 0.95 | SIGMAR1 (0.32) | CCR5 | |
| SCHEMBL7453403 | 0.90 | CCR5 (0.32) | PKMCCR5 | |
| SCHEMBL8102845 | 0.88 | SIGMAR1 (0.34) | PLCG1ALDH1A1 | |
| SCHEMBL7451764 | 0.86 | DPP8 (0.32) | CCR5ALDH1A1MAPTHPGDMMP2 | |
| SCHEMBL7451757 | 0.86 | DPP8 (0.32) | CCR5ALDH1A1MAPTHPGDMMP2 | |
| SCHEMBL8448824 | 0.85 | NR1D1 (0.34) | CCR5ALDH1A1MAPTHPGD | |
| SCHEMBL7457360 | 0.85 | PLCG1 (0.37) | PKMPLCG1CCR5ALDH1A1MAPT | |
| SCHEMBL7453536 | 0.85 | SIGMAR1 (0.33) | CCR5ALDH1A1 | |
| SCHEMBL7454239 | 0.85 | CCR5 (0.31) | CCR5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |