Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SQLE | Q14534 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108789 | 0.94 | ALDH1A1 (0.45) | ALOX15ALDH1A1SQLEGGPS1CBLB | |
| SCHEMBL7567877 | 0.94 | ALDH1A1 (0.45) | ALOX15ALDH1A1SQLEGGPS1CBLB | |
| SCHEMBL8106453 | 0.94 | ALDH1A1 (0.45) | ALOX15ALDH1A1SQLEGGPS1CBLB | |
| SCHEMBL7584379 | 0.94 | ALDH1A1 (0.45) | ALOX15ALDH1A1SQLEGGPS1CBLB | |
| SCHEMBL7561321 | 0.82 | ALOX15 (0.42) | ALOX15ALDH1A1TSHRKDM4EATM | |
| SCHEMBL27545231 | 0.81 | CHRM1 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL7561201 | 0.81 | ALOX15 (0.41) | ALOX15ALDH1A1TSHRKDM4EATM | |
| SCHEMBL5604791 | 0.78 | DNM1 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL7561749 | 0.78 | CYP2D6 (0.47) | ALOX15ALDH1A1TSHRKDM4EATM | |
| SCHEMBL8068621 | 0.77 | SQLE (0.50) | ALOX15ALDH1A1SQLE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |