Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568081 | 0.86 | TTR (0.46) | NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7563386 | 0.85 | NPSR1 (0.43) | NPSR1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7570062 | 0.82 | MMP12 (0.45) | ACACBACACAMEN1KMT2AFFAR1 | |
| SCHEMBL7563170 | 0.78 | NPSR1 (0.45) | NPSR1SMN1; SMN2ACACBACACAMEN1 | |
| SCHEMBL7564712 | 0.74 | TTR (0.48) | NPSR1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7563881 | 0.73 | NPSR1 (0.35) | NPSR1SMN1; SMN2ACACBACACAMEN1 | |
| SCHEMBL7563791 | 0.72 | PTGS1 (0.57) | NPSR1SMN1; SMN2MEN1KMT2AFFAR1 | |
| SCHEMBL7562191 | 0.71 | TTR (0.48) | NPSR1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL2705973 | 0.69 | TTR (0.64) | SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL31644029 | 0.68 | MMP1 (0.51) | SMN1; SMN2MEN1KMT2APOLBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |