Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564712 | 0.88 | TTR (0.48) | NPSR1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7561992 | 0.85 | NPSR1 (0.43) | NPSR1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7562938 | 0.80 | MMP12 (0.48) | MEN1KMT2AHTR1ALMNAFFAR1 | |
| SCHEMBL7568124 | 0.80 | MMP12 (0.48) | MEN1KMT2AHTR1ALMNAFFAR1 | |
| SCHEMBL7563170 | 0.80 | NPSR1 (0.45) | NPSR1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7562191 | 0.76 | TTR (0.48) | NPSR1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL3239506 | 0.74 | NPC1 (0.57) | SMN1; SMN2MEN1KMT2APOLBBCHE | |
| SCHEMBL8886562 | 0.74 | HPGD (0.49) | SMN1; SMN2C5AR1MEN1KMT2APOLB | |
| SCHEMBL30280437 | 0.74 | HPGD (0.49) | SMN1; SMN2C5AR1MEN1KMT2APOLB | |
| SCHEMBL28815272 | 0.72 | CCR5 (0.49) | SMN1; SMN2C5AR1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |