SCHEMBL7562741

SCHEMBL7562741

O=c1oc2ccccc2c2c1CCCC2

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.60
ALDH1A1 P00352 3/20 0.60
HPGD P15428 3/20 0.60
HSD17B10 Q99714 3/20 0.60
CASP1 P29466 2/20 0.60
TSHR P16473 2/20 0.60
GLA P06280 1/20 0.60
GAA P10253 1/20 0.60
CASP7 P55210 1/20 0.60
CYP1A2 P05177 1/20 0.58
MAOA P21397 1/20 0.56
MAOB P27338 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
STS P08842 11/20 0.50
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CYP19A1 P11511 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28360801 0.98 CYP1A2 (0.61) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL11762718 0.96 MAOA (0.60) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL20068157 0.80 ALDH1A1 (0.52) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL2274164 0.79 PARP1 (0.51) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL313890 0.78 CYP3A4 (0.56) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL21587877 0.77 KDM4E (0.69) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL29576889 0.76 MAOA (0.55) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL3628571 0.76 MAOA (0.55) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL3768560 0.75 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10CASP1
SCHEMBL4710494 0.75 ALDH1A1 (0.67) KDM4EALDH1A1HPGDHSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421829-B1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER IND & SANTE (FR) 1994-11-09 EP claimed
US-5169838-A Anticoagulants FOURNIER INDUSTRIE ET SANTE (FR) 1992-12-08 US claimed
EP-0421829-A1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER INDUSTRIE ET SANTE (FR) 1991-04-10 EP claimed
EP-2958906-A1 3-SUBSTITUTED-6H-BENZO[C]CHROMEN-6-ONES AND 3-SUBSTITUTED-7,8,9,10-TETRAHYDRO-6H-BENZO[C]CHROMEN-6-ONES AGAINST SENILE DEMENTIA Nobel Ilaç Sanayii Ve Ticaret A.S. (TR) 2015-12-30 EP disclosed
EP-2958906-A1 3-SUBSTITUTED-6H-BENZO[C]CHROMEN-6-ONES AND 3-SUBSTITUTED-7,8,9,10-TETRAHYDRO-6H-BENZO[C]CHROMEN-6-ONES AGAINST SENILE DEMENTIA Nobel Ilaç Sanayii Ve Ticaret A.S. (TR) 2015-12-30 EP disclosed
WO-2014129989-A1 3-SUBSTITUTED-6H-BENZO[C]CHROMEN-6-ONES AND 3-SUBSTITUTED-7,8,9,10-TETRAHYDRO-6H-BENZO[C]CHROMEN-6-ONES AGAINST SENILE DEMENTIA FARGEM FARMASÖTİK ARAŞTIRMA GELİŞTİRME MERKEZİ SANAYİ VE TİCARET A.Ş. (TR) 2014-08-28 WO disclosed
WO-2014129989-A1 3-SUBSTITUTED-6H-BENZO[C]CHROMEN-6-ONES AND 3-SUBSTITUTED-7,8,9,10-TETRAHYDRO-6H-BENZO[C]CHROMEN-6-ONES AGAINST SENILE DEMENTIA FARGEM FARMASÖTİK ARAŞTIRMA GELİŞTİRME MERKEZİ SANAYİ VE TİCARET A.Ş. (TR) 2014-08-28 WO disclosed
WO-2002028183-A1 FUNGICIDES SYNGENTA LIMITED (GB) 2002-04-11 WO disclosed
EP-0421829-B1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER IND & SANTE (FR) 1994-11-09 EP disclosed
US-5169838-A Anticoagulants FOURNIER INDUSTRIE ET SANTE (FR) 1992-12-08 US disclosed
US-5169838-A Anticoagulants FOURNIER INDUSTRIE ET SANTE (FR) 1992-12-08 US disclosed
EP-0421829-A1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER INDUSTRIE ET SANTE (FR) 1991-04-10 EP disclosed
EP-0421829-A1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER INDUSTRIE ET SANTE (FR) 1991-04-10 EP disclosed
EP-0221293-B1 7,8,9,10-Tetrahydro-6-oxo-6H-dibenzo[b,d]pyranyloxy-propanes PENNWALT CORPORATION (US) 1989-03-08 EP disclosed
US-4681954-A 7,8,9,10-tetrahydro-6-oxo-6H-dibenzo(b,d)pyranyloxy-propanes PENNWALT CORPORATION (US) 1987-07-21 US disclosed
EP-0221293-A1 7,8,9,10-Tetrahydro-6-oxo-6H-dibenzo[b,d]pyranyloxy-propanes PENNWALT CORPORATION (US) 1987-05-13 EP disclosed
US-4647674-A Bis-(dibenzo[b,d]pyranyloxy) propanes PENNWALT CORPORATION (US) 1987-03-03 US disclosed